Core Facility Recent Publications

C.A.Beaudoin, J. Hayes, H. Liu, S. Namadurai, M.J. Deery, E.A. August, S. Krasner, S.W. Hamaia, S.C. Salvage, C.L. Huang, A.P. Jackson, “Structural implications of glycosylation on the voltage-gated sodium channel β3-subunit”, J. Struct Biol. 2026 Jun;218(2):108321. doi: 10.1016/j.jsb.2026.108321. Epub 2026 Apr 23. PMID: 42034256 

K. McCaskie, C. Hutchings, R. Feret, Y.I Kim, L. Breckels, M.J. Deery, K.S. Lilley, “Localization of Organelle Proteins Using Data-Independent Acquisition (DIA-LOP)”, Mol Cell Proteomics. 2025 Sep;24(9):101047. doi: 10.1016/j.mcpro.2025.101047. Epub 2025 Aug 7. PMID: 40783120 

C. Smith, M. Hajisadeghian, G.J.V.H van Noort, M.J. Deery, A. Pinto-Fernández, B.M. Kessler, K. Artavanis-Tsakonas, “Activity-based protein profiling reveals both canonical and novel ubiquitin pathway enzymes in Plasmodium”. PLoS Pathog. 2025 Apr 18;21(4):e1013032. doi: 10.1371/journal.ppat.1013032. eCollection 2025 Apr. PMID: 40249735 

L.T. Hsieh, B.S. Hall, J. Newcombe, T.A. Mendum, S.S. Varela, Y. Umrania, M. J. Deery, W.Q, Shi, J, Diaz-Delgado, F.J. Salguero FJ, R.E. Simmonds, “The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis”. Elife. 2025 Feb 6;12:RP86931. doi: 10.7554/eLife.86931. PMID: 39913180

B. Dirnberger, D. M. Korona, R. Popovic , M. J. Deery, H. Barber, S. Russell, K. S. Lilley, “Enrichment of Membrane Proteins for Downstream Analysis Using Styrene Maleic Acid Lipid Particles (SMALPs) Extraction”” Bio Protoc. 2023 Aug 5;13(15):e4728. doi: 10.21769/BioProtoc.4728. eCollection 2023 Aug 5. PMID: 37575399

M. Baldrighi, C. Doreth, Y. Li, X. Zhao, E. Warner, H. Chenoweth, K. Kishore, Y. Umrania, D.P. Minde, S. Thome, X. Yu, Y. Lu, A. Knapton, J. Harrison, M. Clarke, E. Latz, G. de Cárcer, M. Malumbres, B. Ryffel, C. Bryant, J. Liu, K.S. Lilley, Z. Mallat, X. Li, “XPLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models “, J Clin Invest. 2023 Nov 1;133(21):e162129. doi: 10.1172/JCI162129. PMID: 37698938 

M. Piovesana, A.K.M. Wood, D.P. Smith, M. J. Deery, R. Bayliss, E. Carrera, N. Wellner, O. Kosik, J.A. Napier, S. Kurup, M.C. Matthes “A point mutation in the kinase domain of CPK10 leads to xylem vessel collapse and activation of defence responses in Arabidopsis” J Exp Bot. 2023 May 19;74(10):3104-3121. doi: 10.1093/jxb/erad080..

B Fabre, SA Choteau, C Duboé, C Pichereaux, A Montigny, D Korona D, MJ Deery, M Camus, C Brun, O Burlet-Schiltz, S Russell S, JP Combier, KS Lilley, S Plaza, “In Depth Exploration of the Alternative Proteome of Drosophilamelanogaster” Front Cell Dev Biol.2022 May 26;10:901351. doi: 10.3389/fcell.2022.901351. eCollection (2022).

A Istrate, MB Geeson, CD Navo, BB Sousa, MC Marques, RJ Taylor, T Journeaux, SR Oehler, MR Mortensen, MJ Deery, AD Bond, F Corzana, G Jiménez-Osés, GJL Bernardes, “Platform for Orthogonal N-Cysteine-Specific Protein Modification Enabled by Cyclopropenone Reagents”, 
J Am Chem Soc.;144(23):10396-10406 (2022).

D. Korona , B. Dirnberger, C.N.G. Giachello, RML Queiroz, R., K.H Müller, D.P. Minde, M.J. Deery, G. Johnson, L.C. Firth, F.G. Earley, S. Russell, K.S. Lilley, “Drosophila nicotinic acetylcholine receptor subunits and their native interactions with insecticidal peptide toxins”. Elife10.7554/eLife.74322  (2022).

C. Guffick, P.Y. Hsieh, A. Ali, W. Shi, J. Howard, D,K. Chinthapalli, A.C. Kong, I. Salaa, L.I. Crouch, M.R. Ansbro, S.C Isaacson, H. Singh, N.P. Barrera, A,V, Nair, C.V. Robinson, M.J. Deery MJ, H.W. van Veen, “Drug-dependent inhibition of nucleotide hydrolysis in the heterodimeric ABC multidrug transporter PatAB from Streptococcus pneumoniae”,  FEBS J. 289(13):3770-3788. (2022).

C.M. Mulvey, L.M Breckels, O.M. Crook, D.J. Sanders, A.L.R. Ribeiro, A. Geladaki, A. Christoforou, N.K. Britovšek, T. Hurrell, M.J. Deery, L. Gatto, A.M. Smith, K.S. Lilley, “Spatiotemporal proteomic profiling of the pro-inflammatory response to lipopolysaccharide in the THP-1 human leukaemia cell line”, Nat Commun. 12(1):5773 (2021).

C Erady, A Boxall, S Puntambekar, N Suhas Jagannathan, R Chauhan, D Chong, N Meena, A Kulkarni, B Kasabe, K Prathivadi Bhayankaram, Y Umrania, A Andreani, J Nel, MT Wayland, C Pina, KS Lilley, S Prabakaran. “Pan-cancer analysis of transcripts encoding novel open-reading frames (nORFs) and their potential biological functions” NPJ Genom Med. Jan 25;6(1):4. doi: 10.1038/s41525-020-00167-4 (2021)

L. Carretero-Rodriguez, R. Guðjónsdóttir, I. Poparic, M.L. Reilly, M. Chol, I.H. Bianco, M. Chiapello, R. Feret, M.J. Deery, S. Guthrie S, “The Rac-GAP alpha2-Chimaerin Signals via CRMP2 and Stathmins in the Development of the Ocular Motor System”, J Neurosci.,41(31):6652-6672 (2021).
 

Kamel W, Noerenberg M, Cerikan B, Chen H, Järvelin AI, Kammoun M, Lee JY, Shuai N, Garcia-Moreno M, Andrejeva A, Deery MJ, Johnson N, Neufeldt CJ, Cortese M, Knight ML, Lilley KS, Martinez J, Davis I, Bartenschlager R, Mohammed S, Castello A, “Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection”. Mol Cell, 1;81(13):2851-2867 (2021).

WI Deighan, VJ Winton, RD Melani, LC Anderson, JP McGee, LF Schachner, D Barnidge, D Murray, HD Alexander, DS Gibson, MJ Deery, FP McNicholl, J McLaughlin, NL Kelleher, PM Thomas. “Development of novel methods for non-canonical myeloma protein analysis with an innovative adaptation of immunofixation electrophoresis, native top-down mass spectrometry, and middle-down de novo sequencing.” Clin Chem Lab Med. 59(4):653-661 (2020).

JC Vantourout, SR Adusumalli, KW Knouse, DT Flood, A Ramirez, NM Padial, A Istrate, K Maziarz, JN deGruyter, RR Merchant, JX Qiao, MA Schmidt, MJ Deery, MD Eastgate, PE Dawson, GJL Bernardes GJL, PS Baran, “Serine-Selective Bioconjugation” J Am Chem Soc. 14;142(41):17236-17242 (2020)

K McAulay, EA Hoyt, M Thomas, M Schimpl, MS Bodnarchuk, HJ Lewis, D Barratt, D Bhavsar, DM Robinson, MJ Deery, DJ Ogg, GJL Bernardes, RA Ward, MJ Waring, JG Kettle. “Alkynyl Benzoxazines and Dihydroquinazolines as Cysteine Targeting Covalent Warheads and Their Application in Identification of Selective Irreversible Kinase Inhibitors” J Am Chem Soc. 10;142(23):10358-10372. (2020).